Second Stage 1st Leg
Oriente Petrolero 1-0 Deportes Tolima
Newell's Old Boys 1-0 Estudiantes
Universidad San Martin 2-1 Emelec
Santa Fe 2-1 Caracas FC
Defensor Sporting 9-0 Sport Huancayo
Oriente Petrolero of Bolivia will take a lead into next weeks second game against Desportes Tolima after a single goal was enough to give them victory. Desportes Tolima withstood some heavy pressure but finally cracked ten minutes from time when Mauricio Saucedo grabbed the winner for Oriente Petrolero. Newell's Old Boys also managed to grab a first game advantage when they defeated Estudiantes in Rosario. They left it late though it took a penalty in the third minutes of injury time from Mauro Fórmica to give them victory. Peru's Universidad San Martin will also take an advantage to the altitude of Emelec after a 2-1 first game victory. It all started well for the Ecuadorians when Joao Rojas put them ahead with just four minutes on the clock but Pablo Vitti levelled matters just before half time. Emelec then had Gabriel Achilier sent off four minutes after the break and Ronald Quinteros put Universidad San Martin ahead with sixteen minutes left. The night ended on a sour note for Emelec when they had Mariano Mina sent off four minutes from time.
Santa Fe of Colombia were another team to come from behind as they defeated Caracas FC of Venezuela. Heatklif Castillo put Caracas ahead eight minutes before the break but Luis Seijas levelled matters ten minutes into the second half. Óscar Rodas got the winner for Santa Fe eighteen minutes from time. Defensor Sporting of Uruguay are all but into the last 16 as they went goal crazy against Sport Huancayo of Peru. Defensor were ahead with a minute on the clock when Diego De Souza converted from the penalty spot. Sport Huancayo then had Blas Lopez sent off five minutes before the break and Mario Risso doubled the lead a minute before the break. Two goals in a minute just after the break, a second for De Souza and Miguel Amando made it four before Rodrigo Mora got the fifth on 56 minutes. Adrian Luna converted from the spot on the hour to make it six and then Sport Huancayo had Javier Salazar sent off to reduce them to nine. A second for Rodrigo Mora, this time from the spot made it seven before Eduardo Aranda and a second from Luna completed the scoring.
Second Stage 2nd Leg
Peñarol 2-1 Barcelona
Peñarol advances 6-0 on points
Banfield 1-1 Vélez Sársfield
Banfield advances 4-1 on points
Uruguay's Peñarol advanced into the round of 16 and a clash with Goiás after a 2-1 success at home to Barcelona of Ecuador. Joonatan Ramis put Peñarol into the lead with eighteen minutes to go but after an own goal from Sebastian Sosa with 11 minutes to go gave Barcelona hope as they were a goal way from qualification. As Barcelona pressed, Peñarol made the tie safe in injury time wen Antonio Pacheco slotted home from the spot. Banfield made it into the round of 16 and clash with either Oriente Petrolero or Deportes Tolima after knocking Vélez Sársfield. A game that saw four red cards, finished level on the goals but Vélez won the card count. Marcelo Carrusca put Banfield ahead with a quarter of an hour but as Vélez chased the game they lost Fernando Ortiz, Santiago Silva and Leandro Somoza to red card within an 18 minute period. Carrusca then got a red card to go along with his goal five minutes to go but Jonathan Cristaldo levelled the tie on the night but it wasn't enough to see Vélez through.